(1) several members of the family are known to have lentigo(2) However, some lentigines are associated with systemic abnormalities, in addition to the dermatologic manifestations.(3) The 755 nm wavelength can be used to treat solar lentigines .(4) The best way to prevent lentigines is to stay out of the sun as much as possible.(5) Multiple lentigines in the skin, lips, and mucous membranes should raise suspicion for Peutz-Jeghers syndrome.(6) Although occasionally lentigines are part of a rare genetic syndrome, for the most part they are just isolated and unimportant spots.
